Just remember to ensure you have a backup solution in place so you don't lose your email data.
This can be an important consideration for business purposes, as allowing your email to run through web apps means that although it will be safely backed-up, it also means the provider has control over your data, and some companies openly acknowledge that they will scan private emails at least for marketing purposes. In other words, only you control your emails, and third-parties have no access to them unless you purposefully - or accidentally - allow it.
While email clients may require a little more work to run, they also allow for more control over user data. There are many different office software suites but Google Workspace formerly known as G Suite remains the original cloud one and one of the best business office suites, offering a huge range of features and functionality that rivals can't match. Google Workspace : Collaboration + productivity apps